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Skin conditioning agent

DIETHYL KETOGLUTARATE

72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An ester of alpha-ketoglutaric acid used as a lightweight skin-conditioning agent. It softens the surface, supports moisture retention, and leaves a silky non-greasy finish in moisturisers and after-sun lotions.

Skin benefits

  • Acts as a skin conditioner that softens and smooths the skin surface
  • Supports moisture retention for a non-greasy silky finish
  • Derivative of alpha-ketoglutarate, a natural Krebs-cycle metabolite
  • Generally well tolerated across skin types including sensitive skin

Known concerns

  • Limited independent regulatory safety review (no CIR or SCCS opinion located)
  • Long-term topical safety data is sparse
  • Possible mild irritation in those sensitive to ester ingredients

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related skin conditioning agents

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.