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DIETHYL KETOGLUTARATE

68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Diethyl Ketoglutarate is a cosmetic ingredient. Exercise caution due to limited available safety data.

Diethyl Ketoglutarate is the diethyl ester of 2-oxoglutaric acid (alpha-ketoglutaric acid), functioning as a skin conditioning agent and fragrance. The keto-dicarboxylic acid is a natural intermediate in the Krebs cycle, suggesting good metabolic compatibility. Diethyl esters are generally well-tolerated and not restricted in EU cosmetics, though the ester bond can hydrolyse on skin.

Skin benefits

  • Skin conditioning — emollient
  • Metabolically compatible — natural TCA cycle intermediate

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.