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Skin conditioning agent

PICOLINAMIDE

CAS 1452-77-3
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Picolinamide is a pyridine-2-carboxamide closely related to niacinamide, explored as a skin-conditioning and antioxidant active. It is less established in cosmetic use than niacinamide but appears generally well tolerated.

Skin benefits

  • Related to niacinamide chemistry with potential skin-conditioning effects
  • May offer mild antioxidant activity
  • Used as a research-stage cosmetic active in some Asian formulations

Known concerns

  • Less mainstream than niacinamide with thinner safety record
  • Limited large-scale clinical data in cosmetics
  • Potential for sensitivity in users reactive to pyridine derivatives

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related skin conditioning agents

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.