PICOLINAMIDE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
PICOLINAMIDE is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.
Picolinamide is the amide of picolinic acid (a niacin/nicotinic acid derivative), functioning as a fragrance ingredient with mild nutty and pyridine-like notes. The pyridine ring confers some biological activity, and picolinic acid derivatives have been studied for metal-chelating properties. This ingredient is not listed on EU Annex restrictions and carries no GHS hazard statements. However, the structural similarity to niacin (vitamin B3) raises questions about potential pharmacological effects at high concentrations.
Skin benefits
- May provide mild skin-conditioning effects due to niacinamide-like structure
Known concerns
- Structural similarity to pharmacologically active pyridine derivatives warrants scrutiny
- No specific EU cosmetic restrictions
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.