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Fragrance

Diethyl maleate, when used as a fragrance ingredient

CAS 141-05-9
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Diethyl maleate when used as a fragrance ingredient — a reactive Michael-acceptor ester recognised as a skin sensitizer. EU and IFRA restrict its use; concentrations above the limit must be avoided in leave-on products.

Skin benefits

  • Fragrance modifier in trace amounts

Known concerns

  • Established skin sensitizer
  • IFRA/RIFM restriction
  • Michael-acceptor reactivity with skin proteins

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.