Other
DIHYDRONIACINAMIDE RIBOSIDE ACETYL TRI-T-BUTYL TRYPTOPHANATE
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A multi-component vitamin B3 (niacinamide) and tryptophan derivative designed for enhanced skin delivery and stability, with a favourable safety profile expected from its well-tolerated parent compounds.
This is a complex molecular conjugate combining dihydronicotinamide (a reduced form of niacinamide/vitamin B3) with a t-butyl-protected tryptophan moiety via an acetyl linker. Niacinamide itself is extensively studied, well-tolerated in cosmetics, and listed in EU CosIng without restrictions. The t-butyl tryptophan fragment is a protected amino acid derivative — the t-butyl ester and amide protections are chemically stable under cosmetic use conditions and are fragments of widely-used pharmaceutical protecting groups with no intrinsic toxicity. The overall conjugate is expected to have an excellent safety profile consistent with its vitamin B3 heritage.
Skin benefits
- Enhanced skin delivery of niacinamide via conjugate design
- Potential antioxidant and anti-aging benefits from both B3 and tryptophan fragments
- Stable protected form unlikely to cause flushing
Known concerns
- Complex novel conjugate — limited specific in vivo safety data
- No EU CosIng specific restriction entries identified
- Broadly regarded as safe based on parent compound toxicology
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
Check your shelf
Find DIHYDRONIACINAMIDE RIBOSIDE ACETYL TRI-T-BUTYL TRYPTOPHANATE in your products.
Scan any cosmetic product with LuxSense to see if it contains DIHYDRONIACINAMIDE RIBOSIDE ACETYL TRI-T-BUTYL TRYPTOPHANATE and get a full ingredient breakdown with safety scores.
This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.