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Dimethylcarbamoyl chloride

CAS 79-44-7
0

Safety score · 0–100

Not Rated

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An industrial acyl chloride reagent. Classified as a Cat. 1B carcinogen in the EU and acutely toxic — categorically not a cosmetic ingredient.

Dimethylcarbamoyl chloride (DMCC, CAS 79-44-7) is an industrial synthesis reagent used to install dimethylcarbamoyl groups onto pharmaceuticals and agrochemicals. It is IARC Group 2A (probably carcinogenic to humans) and EU CLP harmonised-classified as Carc. 1B (H350) and Acute Tox. 3 (H331, toxic if inhaled). It is a REACH Substance of Very High Concern (SVHC) and thus automatically prohibited in cosmetics under the CMR mechanism (EU Cosmetics Regulation Annex II by reference). Chemically it hydrolyses violently on water contact, releasing HCl and dimethylamine, which rules out aqueous cosmetic matrices on basic chemistry alone. Its appearance in a cosmetic-ingredient database is regulatory watch-listing, not a formulation ingredient.

Skin benefits

  • None

Known concerns

  • IARC Group 2A probable carcinogen
  • CLP Carc. 1B and acute inhalation toxicity
  • REACH SVHC
  • Chemically incompatible with aqueous cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.