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Fragrance

DIMETHYLHYDROQUINONE

CAS 150-78-7
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A dimethylated hydroquinone — a compound class with serious cosmetic restriction history and best avoided.

2,5-Dimethylhydroquinone (CAS 95-71-6) and related dimethyl isomers are substituted hydroquinones — a chemical class strictly regulated in cosmetics. Unsubstituted hydroquinone is banned in EU cosmetics (Annex II) and its use as a leave-on cosmetic is restricted in most jurisdictions because of ochronosis, contact sensitization, irritation, and concerns about mutagenicity. Methylated hydroquinones can still undergo oxidative activation and have antioxidant/redox activity, so regulators have historically been cautious about their cosmetic use. Although this specific compound is sometimes listed as a fragrance, hydroquinone-class labeling alone is enough to reduce confidence; conservative practice is to avoid it in modern cosmetic formulations.

Function

PERFUMING

Skin benefits

  • Historical use as antioxidant/stabilizer
  • May contribute an olfactory role at trace levels

Known concerns

  • Hydroquinone-class compound — skin-lightening concern
  • Hydroquinone is restricted/banned as cosmetic leave-on ingredient in EU and heavily regulated elsewhere
  • Potential for ochronosis, sensitization, and tissue damage
  • Dimethylated variant may still undergo oxidative or metabolic activation
  • Not considered a safe cosmetic ingredient

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.