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Dobutamine hydrochloride [USAN:BAN:JAN]

CAS 49745-95-1
12

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Dobutamine hydrochloride [USAN:BAN:JAN] is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Dobutamine is a synthetic catecholamine (3,4-dihydroxy-N-[3-(p-hydroxyphenyl)-1-methylpropyl]-phenethylamine) with direct positive inotropic activity on cardiac beta-1 receptors. It is administered by intravenous infusion in hospital settings for acute decompensated heart failure and cardiogenic shock. Its pharmacological activity as a cardiovascular agent is entirely incompatible with cosmetic use. The EU Cosmetics Regulation does not include dobutamine in any positive list; its prescription drug status and hospital-only administration preclude any cosmetic formulation role.

Known concerns

  • Potent cardiovascular drug – IV hospital use only
  • Beta-1 adrenergic agonist with significant cardiac effects
  • Prescription-only medicine – no cosmetic application
  • Not evaluated or authorized under EU cosmetic regulations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.