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ESTRADIOL

CAS 50-28-2
3

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Estradiol is a prescription female hormone, banned in EU cosmetics. It is a strong endocrine disruptor and has no legitimate place in skincare.

Function

SKIN CONDITIONING

Skin benefits

  • No legitimate cosmetic benefit

Known concerns

  • EU Annex II banned in cosmetics
  • Potent estrogenic hormone
  • Endocrine disruption
  • Carcinogenic via hormonal pathways
  • Prescription-only medicine, not a cosmetic

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.