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ETHYL THIOGLYCOLATE

CAS 623-51-8
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Ethyl Thioglycolate is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Ethyl thioglycolate is restricted under EU Cosmetics Regulation Annex III (reference III/2b), which imposes strict concentration limits as it is used in hair waved or straightened products that are rinsed off after use. It is a known skin sensitizer and has been associated with neurotoxicity concerns with repeated exposure. The thioglycolate moiety raises mutagenicity flags; the SCCS has established safe concentration limits for this substance. Professional use is typically advised, and home-use formulations face particular scrutiny under EU regulations.

Known concerns

  • skin sensitizer (strong) — EU Annex III restricted
  • neurotoxicity concern with repeated exposure
  • mutagenicity flags for the thioglycolate moiety
  • restricted in EU for rinse-off hair products only

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.