Solvent
Ethylene glycol monobutyl ether (EGBE)
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A glycol-ether solvent (CAS 111-76-2) better known from industrial cleaning. Metabolises to a haematotoxic acid in vivo and carries EU concentration restrictions in cosmetics — modern formulators avoid it entirely.
Skin benefits
- Effective coupling solvent for surfactant systems
- Useful in industrial and household cleaners
- Cheap and widely available
Known concerns
- Metabolised to butoxyacetic acid — haematotoxic in animals
- Reproductive and developmental toxicity flags in EU SCCS reviews
- EU restricts use in cosmetics, particularly aerosol formats
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related solvents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.