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Antioxidant

GALLOYL SH-PENTAPEPTIDE-4 AMIDE

82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A galloyl-conjugated pentapeptide, combining a polyphenol-style antioxidant warhead with a signal peptide. Class shows clean dermal tolerance, used at low ppm in leave-on antioxidant serums.

Function

ANTIOXIDANTSKIN PROTECTING

Skin benefits

  • Free-radical quenching from galloyl moiety
  • Skin conditioning via pentapeptide-4 signalling
  • Useful in anti-pollution and anti-ageing formats

Known concerns

  • Galloyl esters may hydrolyse during shelf-life
  • Limited independent SCCS/CIR data
  • Possible mild sensitisation in reactive skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.