Other
HESPERETIN
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Hesperetin is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.
Hesperetin is a flavanone (a subclass of flavonoid) predominantly found in citrus fruits, especially oranges and lemons. It exhibits strong antioxidant activity, anti-inflammatory effects, and vasoprotective properties. Hesperetin and its glycoside form hesperidin are permitted cosmetic ingredients under EU Regulation 1223/2009 with no specific restriction. Naturally derived hesperetin is considered safe with a low incidence of adverse effects, though synthetic or highly concentrated forms warrant purity evaluation.
Skin benefits
- Antioxidant protection from free radical damage
- Anti-inflammatory skin calming
- Supports skin elasticity and collagen
- May help reduce capillary permeability
Known concerns
- Generally well-tolerated; minimal concerns
- Source and purity should be verified for synthetic forms
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.