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Hexahydro-1,2-dimethyl-4-phenyl-4-azepinecarboxylic acid methyl ester

CAS 469-78-3
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic opioid-class compound (ethoheptazine/meptazinol scaffold) — a prescription pharmaceutical, not a cosmetic ingredient. EU Annex II prohibits it. Banned-tier rating.

Skin benefits

  • No legitimate cosmetic benefit — pharmacologically active opioid/analgesic compound

Known concerns

  • Pharmacologically active opioid analgesic scaffold
  • EU Annex II prohibited substance for cosmetics (narcotics, listed)
  • Serious systemic toxicity if absorbed
  • Misuse potential

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.