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HUMAN ADIPOSE STROMAL CELL CONDITIONED MEDIA WATER

52

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A steam-distilled aqueous form of human adipose stromal cell conditioned media, where the water-soluble secreted factors are captured in a hydrosol format.

Human adipose stromal cell conditioned media water is the aqueous distillate of the conditioned media, regulated under EU Annex II/416 as a material of human origin. The distillation process may concentrate certain volatile secreted compounds while removing cells and large proteins. This water-soluble format may offer slightly better regulatory acceptance as the active ingredients are in solution rather than as a complex cell-derived material. Full Annex II/416 compliance is still required.

Skin benefits

  • Water-soluble fractions of adipose stromal secretions captured in hydrosol
  • May contain cytokines and small molecule metabolites from stromal cells
  • Easier to formulate in aqueous cosmetic bases

Known concerns

  • EU Annex II/416 restriction
  • Distillation may concentrate undefined compounds
  • Pathogen screening required from adipose tissue source
  • FBS carry-over from culture medium possible

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.