Hydroxyethyl-3,4-methylenedioxyaniline and its hydrochloride
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A cosmetic ingredient. Exercise caution due to limited available safety data.
Hydroxyethyl-3,4-methylenedioxyaniline is listed in Annex III of EU Regulation (EC) No 1223/2009, restricting its use to oxidative hair dye formulations. The methylenedioxyaniline structure is structurally related to safrole derivatives. As with all aromatic amine hair dye intermediates, there are concerns about potential genotoxicity and skin sensitization. Its use in hair dye formulations must be followed by thorough rinsing. It is restricted to professional use only in EU member states.
Skin benefits
- Used as an oxidative hair dye intermediate providing color development in professional hair dye products
Known concerns
- EU Annex III restricted to oxidative hair dye formulations
- Professional use only
- Potential skin sensitization
- Structurally related to safrole derivatives requiring caution
- Thorough rinsing required after use
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.