N,N'-DIMETHYL-N-HYDROXYETHYL-3-NITRO-P-PHENYLENEDIAMINE
Other
Caution
CAS Number: 10228-03-2
About N,N'-DIMETHYL-N-HYDROXYETHYL-3-NITRO-P-PHENYLENEDIAMINE
A nitro-substituted phenylenediamine used as a hair dye intermediate, restricted under EU regulations for oxidative hair dye applications.
Detailed Analysis
This nitro-phenylenediamine derivative is regulated under EU CosIng restriction II/1288, indicating it may be used in hair dye products only under specific conditions and at controlled concentrations. Compounds with nitro groups on the aromatic ring are of concern due to potential mutagenicity. The EU SCCS has assessed similar p-nitro-phenylenediamine derivatives and imposed concentration limits for safe use.
Skin Benefits
- ✓ Functions as a primary hair dye intermediate providing color
Known Concerns
- ⚠ EU CosIng restriction II/1288 — permitted only under specified conditions for hair dyes
- ⚠ Potential mutagenicity concern from nitro-aromatic structure
- ⚠ Skin sensitization risk, particularly in individuals with para-phenylenediamine (PPD) allergy
Safety Score
Caution
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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