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HYDROXYPROPYLTRIMONIUM HYDROLYZED COLLAGEN
Safety score · 0–100
Excellent
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A well-established cationic hydrolyzed collagen derivative used across cosmetic categories for skin smoothing, film-forming hydration, and hair conditioning.
Hydroxypropyltrimonium Hydrolyzed Collagen (CAS 11308-59-1, 83138-06-1, 111174-62-0) is prepared by partial enzymatic hydrolysis of collagen (typically bovine or porcine) followed by chemical modification to introduce hydroxypropyl and trimethylammonio groups. The resulting quaternary ammonium-modified protein has reduced molecular weight for skin compatibility while retaining film-forming and water-binding properties of native collagen. Hydrolyzed collagen and its cationic derivatives are among the most extensively studied and historically used cosmetic ingredients, approved in all major regulatory jurisdictions including EU Annex VI (preservatives not applicable — it is not a preservative). The ingredient has an excellent safety record in leave-on and rinse-off products.
Skin benefits
- Intense moisturization from water-binding hydroxyproline residues
- Film-forming creates protective barrier on skin and hair
- Improves skin elasticity and smoothness
- Conditions and reduces static in hair care formulations
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.