Other
ISORHAMNETIN
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Isorhamnetin is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.
Isorhamnetin is a methylated flavonol found in many plants including sea buckthorn and various medicinal herbs. It shares the general safety profile of the flavonol class — no GHS hazard statements, no CosIng restrictions. The compound has documented antioxidant activity (comparable to or slightly less potent than quercetin), anti-inflammatory activity via NF-κB pathway inhibition, and potential matrix metalloproteinase inhibition relevant to anti-aging formulations. No safety concerns have been raised by SCCS or other regulatory bodies.
Skin benefits
- Antioxidant activity protects against free radical and UV-induced skin damage
- Anti-inflammatory properties soothe reactive or sensitive skin
- May inhibit collagen-degrading matrix metalloproteinases (MMP-1)
- Quercetin-like photoprotective properties when used in sunscreen formulations
Known concerns
- Generally very safe; rare flavonoid allergy possible in sensitized individuals
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.