Skin Conditioning
KERATINASE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A protein-cleaving enzyme that breaks down keratin — used for chemical exfoliation, callus softening and depilatory work. Effective but proteolytic, so irritation and respiratory allergy risk to handlers are real.
Skin benefits
- Enzymatic exfoliation by degrading keratin
- Softens calluses and stratum corneum
- Used in depilatory and hair-conditioning systems
- Specific mode of action — alternative to mechanical scrubs
Known concerns
- Active proteolytic enzyme — irritation/sensitization risk
- Inhalation hazard from spray-dried enzyme dust
- Respiratory allergen for handlers
- Activity can overshoot at higher inclusion
- Stability and shelf-life limit formulation
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.