Other
MANGOSTIN
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Mangostin is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.
Mangostin is a major prenylated xanthone isolated from the pericarp of Garcinia mangostana (mangosteen). It exhibits strong antioxidant activity by scavenging free radicals, along with anti-inflammatory effects via COX-2 and NF-κB inhibition pathways. It is listed in the CosIng database with no EU restrictions and is used in anti-aging and brightening skincare formulations. Available toxicological data support its safety at cosmetic usage levels.
Skin benefits
- Potent antioxidant activity against free radicals
- Anti-inflammatory properties via COX-2 inhibition
- Antimicrobial effects useful in acne-prone skin formulations
- Used in anti-aging and brightening skincare products
Known concerns
- No significant EU regulatory restrictions
- Natural extract — potential variation in composition
- Rare contact allergy reported in highly sensitized individuals
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.