Botanical active
MATRINE GALLATE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Plant-derived hybrid combining matrine alkaloid from Sophora flavescens with gallic acid ester. Used at low levels for anti-inflammatory and antimicrobial support in acne-targeted skincare formulations.
Skin benefits
- Matrine moiety provides anti-inflammatory activity
- Gallate ester contributes antioxidant capacity
- Studied for acne-prone skin support
- May reduce microbial burden on skin
Known concerns
- Matrine is an alkaloid with potential systemic toxicity at higher exposures
- No SCCS or CIR safety assessment for this specific ester
- Limited published cosmetic safety data
- Quality and purity highly source-dependent
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related botanical actives
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.