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Conditioning Agent

METHIONYL SH-POLYPEPTIDE-1

82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A recombinant human protein produced in E. coli — designed for advanced skin conditioning applications.

Methionyl sh-Polypeptide-1 is a single-chain synthetic peptide produced by bacterial fermentation in E. coli, with a methionyl initiation codon added to the human gene sequence. It functions as a skin conditioning agent. No GHS hazards, no EU restrictions. Recombinant proteins used in cosmetics are highly purified and used at trace levels, minimizing immunogenicity concerns.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning
  • Bioactive protein activity

Known concerns

  • Recombinant protein — theoretical immunogenicity
  • Limited clinical data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related conditioning agents

Same plant / compound family

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.