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Skin Conditioning

METHIONYL SH-POLYPEPTIDE-14 DECAPEPTIDE-40

60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A lab-made polypeptide combo (methionyl SH-polypeptide-14 with decapeptide-40). Trace-use peptide; safety is reasonable at typical levels but the dossier is thin.

Skin benefits

  • Peptide signaling claim per supplier
  • Low use level keeps irritation risk low
  • Compatible with most aqueous serums

Known concerns

  • Synthetic polypeptide with no CIR/SCCS file
  • Marketing-led efficacy claims
  • Manufacturer-dependent purity profile

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.