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Skin Conditioning

METHIONYL SH-POLYPEPTIDE-59 DECAPEPTIDE-40

60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A lab-made polypeptide blend (methionyl SH-polypeptide-59 with decapeptide-40). Trace-use peptide; plausible safety at typical levels with limited public dossier.

Skin benefits

  • Targeted peptide signaling per supplier
  • Trace use limits irritation risk
  • Stable in modern formulations

Known concerns

  • Synthetic polypeptide with no CIR/SCCS file
  • Efficacy claims outpace independent data
  • Manufacturer-dependent purity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.