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Skin Conditioning

METHIONYL SH-POLYPEPTIDE-76 DECAPEPTIDE-40

60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A lab-made polypeptide (methionyl SH-polypeptide-76 paired with decapeptide-40). Trace-use peptide with marketing-led efficacy claims and limited independent safety dossier.

Skin benefits

  • Targeted peptide signaling claim by suppliers
  • Used at trace level so low irritation risk
  • Stable in modern formulations

Known concerns

  • Recombinant/synthetic peptide with proprietary biology and no public CIR/SCCS file
  • Efficacy claims often outpace published evidence
  • Quality and contaminant profile depends on the manufacturer

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.