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Banned Substance

methoxamine

CAS 390-28-3
4

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An alpha-1 adrenergic vasoconstrictor drug used historically to support blood pressure. Listed in EU Annex II — banned in cosmetics. Pharmaceutical-only with marked cardiovascular effects.

Skin benefits

  • No legitimate benefit in cosmetics — banned

Known concerns

  • EU Annex II banned medicinal substance
  • Alpha-1 adrenergic agonist drug
  • Cardiovascular pressor effects
  • Pharmaceutical, not cosmetic

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.