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METHOXY PEG-450 MALEIMIDE

50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A PEG-tethered maleimide used as a peptide-conjugation reagent, sometimes carried into finished products in trace amounts. Maleimide groups are reactive and sensitizing, so we default down.

Function

HAIR CONDITIONINGSURFACTANT - CLEANSING

Skin benefits

  • Used as a peptide-coupling/conjugation reagent
  • Adds PEG modification to peptides
  • Functional in trace amounts

Known concerns

  • Maleimide group is reactive (Michael acceptor) and a known sensitizer
  • Trace residual maleimide can irritate skin
  • Limited cosmetic-specific safety data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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Same plant / compound family

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METHOXY PEG-450 AMIDO HYDROXYSUCCINIMIDYL SUCCINAMATE
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.