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METHOXYACETOPHENONE

CAS 100-06-1
78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Methoxyacetophenone is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Methoxyacetophenone (4'-methoxyacetophenone or anisacetone) is an aromatic ketone used as a fragrance ingredient in cosmetics and fine fragrances. The EU CosIng database lists it without restrictive entries, and it is recognized by IFRA (International Fragrance Association) as safe for use within standard concentration limits. The compound has been reviewed by the EU SCCS and by RIFM (Research Institute for Fragrance Materials) for dermatological safety, with a conclusion of low concern at current consumer exposure levels in rinse-off and leave-on applications.

Skin benefits

  • Sweet, anisic fragrance profile used in floral and oriental perfume compositions
  • Acts as a fragrance fixative improving substantivity

Known concerns

  • Minor skin sensitization reported at high concentrations (rare at typical fragrance use levels)
  • IFRA standards specify maximum use levels in various product categories
  • Fragrance allergen declaration threshold applies in the EU above 0.01%

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.