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METHYL 2,6,10-TRIMETHYLCYCLODODECA-2,5,9-TRIENYL KETONE

CAS 28371-99-5
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A macrocyclic ketone fragrance with significant skin sensitization warnings and aquatic toxicity that faces EU allergen restrictions.

This macrocyclic ketone is a fragrance compound with multiple hazard classifications including skin sensitization (H317), skin irritation (H315), eye irritation (H319), and serious aquatic toxicity (H410/H411). The EU Scientific Committee on Consumer Safety (SCCS) has flagged macrocyclic ketones as potent sensitizers requiring concentration limits in cosmetic products typically capped at safe levels established in IFRA standards.

Skin benefits

  • fragrance function

Known concerns

  • skin sensitizer (H317)
  • skin irritant (H315)
  • eye irritant (H319)
  • aquatic toxic (H410/H411)
  • potent allergen

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.