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Active Ingredient

METHYL ESTRADIOLPROPANOATE

CAS 345295-00-3 Updated
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A propanoate ester derivative of the hormone estradiol. Estrogens and their esters are EU Annex II banned cosmetic substances due to clear endocrine disruption risk — never appropriate in cosmetic products.

Function

SKIN CONDITIONING - EMOLLIENTSKIN CONDITIONING

Skin benefits

  • Steroid-class skin conditioning effects in pharmaceutical contexts

Known concerns

  • Estradiol derivatives are EU Annex II banned hormonally active substances
  • Endocrine disruption risk via skin absorption
  • Pharmaceutical-only use, not appropriate for cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.