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Skin Conditioning

METHYL GLYCYRRHIZATE

CAS 104191-95-9 Updated
78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A methyl ester of glycyrrhizic acid (the active in licorice root), used in fragrance and skincare for its soothing, sweet-amber character. Generally well tolerated, with limited public data on this exact ester holding it in upper Yellow.

Function

FRAGRANCE

Skin benefits

  • Licorice-derived ester with skin-soothing and anti-inflammatory pedigree
  • Adds amber, slightly sweet character in fragrance applications
  • Glycyrrhizin family has long traditional use in Asian skincare

Known concerns

  • Limited cosmetic-specific safety dossier on the methyl ester variant
  • Glycyrrhizin family at high oral doses raises blood pressure — irrelevant topically but noted
  • Possible mild sensitisation in licorice-allergic users

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.