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METHYL PYRAZINYL KETONE

CAS 22047-25-2
62

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Methyl Pyrazinyl Ketone is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Methyl pyrazinyl ketone (2-acetylpyrazine) is a pyrazine derivative used as a fragrance ingredient imparting a characteristic popcorn, nutty, or toasted aroma. It occurs naturally in foods and is approved as a flavouring substance. From a toxicological standpoint, pyrazines are generally low in acute toxicity. No EU cosmetic restrictions apply to 2-acetylpyrazine specifically, though it must comply with general safety requirements under Regulation 1223/2009.

Skin benefits

  • Provides distinctive fragrance (popcorn, nut, toast notes) in cosmetic products
  • Contributes to complex aromatic profile in fine fragrances

Known concerns

  • May cause mild irritation at high concentrations
  • Pyrazine heterocycle — limited specific cosmetics toxicology data
  • Must comply with general EU cosmetic safety assessment requirements

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.