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methyldihydromorphine

CAS 509-56-8
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Methyldihydromorphine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Methyldihydromorphine is a semisynthetic opioid analgesic derived from morphine, with pharmacological activity as a mu-opioid receptor agonist producing analgesia and CNS depression. Its CAS number 509-56-8 is specifically listed in EU Annex II (banned substances) under Regulation (EC) No 1223/2009, prohibiting its presence in cosmetic products. As a controlled substance with significant abuse potential and respiratory depression risk, it has no place in cosmetic formulations under any circumstances.

Known concerns

  • EU Annex II banned — CAS 509-56-8 specifically prohibited
  • Potent opioid analgesic — completely unsuitable for cosmetics
  • CNS depression and respiratory depression risk
  • Controlled substance with high abuse potential

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.