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methyltestosterone

CAS 58-18-4
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Methyltestosterone is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Methyltestosterone (17α-methyl-4-androsten-17β-ol-3-one) is a potent orally-active androgen with well-documented hepatotoxic and endocrine-disrupting effects. It is listed on EU Cosmetics Regulation Annex II (banned substances) as a CMR Category 1B substance (H360 — May damage fertility or the unborn child). The SCCS has never assessed it as safe for cosmetic use, and its presence in any cosmetic formulation constitutes a serious regulatory violation.

Known concerns

  • EU Annex II banned — CMR substance H360 (reproductive toxicity)
  • Hepatotoxic effects
  • Endocrine disruption — androgenic hormone

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.