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metopon

CAS 143-52-2
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Metopon is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Metopon (CAS 143-52-2) is a methylated morphine derivative (6-methyldihydromorphine) with potent opioid analgesic activity, historically used in pain management. As a controlled opioid substance with significant CNS and respiratory depression effects, it has no place in cosmetic formulations. EU regulations classify it as a pharmaceutical substance of concern, and it is not listed in CosIng as a cosmetic ingredient. Any presence in a cosmetic product would represent a serious regulatory and safety violation.

Known concerns

  • Potent opioid analgesic — completely incompatible with cosmetic use
  • Risk of systemic opioid effects from topical absorption
  • Not a cosmetic ingredient under any regulatory framework

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.