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N-(5-Chlorobenzoxazol-2-yl)acetamide

CAS 35783-57-4
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

N-(5-Chlorobenzoxazol-2-yl)acetamide is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

N-(5-Chlorobenzoxazol-2-yl)acetamide is a chlorinated benzoxazole derivative with an acetamide substituent, producing a heterocyclic ring system with known biological activity profiles for benzoxazoles. No EU Annex restriction, GHS hazard statements, or INCI safety assessment are available. The benzoxazole scaffold is associated with antimicrobial and enzyme-inhibitory activity, and the 5-chloro substituent adds lipophilicity. Without comprehensive toxicological data, this ingredient must be treated as a structure of concern in cosmetic formulations.

Known concerns

  • Limited toxicological data for cosmetic use
  • Benzoxazole ring system – structural alert for biological activity
  • 5-chloro substituent increases lipophilicity and potential for skin penetration
  • No EU safety assessment on record

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.