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NIACINAMIDE MANDELATE

83

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

The salt of niacinamide (vitamin B3) and mandelic acid (an alpha hydroxy acid), combining two well-studied skin-benefiting agents into a single mild molecule.

Niacinamide mandelate is the salt formed from niacinamide (vitamin B3) and mandelic acid (an aromatic alpha-hydroxy acid derived from almonds). Both parent compounds are extensively studied, well-tolerated cosmetic ingredients. Niacinamide supports barrier repair, reduces hyperpigmentation, and modulates sebum; mandelic acid provides gentle exfoliation and skin renewal. The salt form may moderate the acidity of mandelic acid, potentially reducing irritation while delivering both actives. No CAS number or specific EU restriction is documented for this salt form, but neither parent compound is restricted.

Skin benefits

  • Niacinamide component — barrier strengthening, pore minimising, brightening
  • Mandelic acid component — gentle alpha-hydroxy exfoliation, skin renewal
  • Combined action — addresses uneven skin tone, texture, and mild acne
  • Milder than free mandelic acid — reduced irritation potential

Known concerns

  • Alpha-hydroxy acid component — may increase sun sensitivity (use SPF protection)
  • No specific CAS or EU CosIng entry — salt form requires individual safety review
  • Generally well-tolerated but patch testing advised for sensitive skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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COCAMIDOPROPYL MORPHOLINE LACTATE
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ERUCAMIDE
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ETHYL 2,4-DICARBOETHOXY PANTOTHENATE
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ETHYL CINNAMATE
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.