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Conditioning Agent

NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-POLYPEPTIDE-6

58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A plant-made recombinant fusion peptide with real bioactivity but very limited public cosmetic safety history.

This is a transgenic Nicotiana benthamiana-produced fusion peptide that includes a human cytokine-like segment. Ingredients this bioactive are used at low levels, but they sit well outside the usual comfort zone of bland moisturizers and have limited long-term public cosmetic data, so a cautious middle score fits best.

Function

SKIN CONDITIONING

Skin benefits

  • May support calmer-looking skin

Known concerns

  • Highly bioactive ingredient class
  • Limited long-term public safety data
  • Potential immunologic uncertainty

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related conditioning agents

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.