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Skin Conditioning

NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-POLYPEPTIDE-9

CAS 127464-60-2 Updated
60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A tobacco-plant-grown fusion peptide blending a VEGF-A-mimic with Hexapeptide-40. Innovative manufacture but a growth-factor mimic in cosmetics warrants caution — solid yellow.

Function

HAIR CONDITIONING

Skin benefits

  • Plant-based recombinant peptide production
  • VEGF-A-mimic motif targets anti-aging claims
  • Hexapeptide-40 conditioning effects
  • Lower endotoxin risk than E. coli-produced fusion peptides

Known concerns

  • Growth-factor mimic in cosmetics carries activity-vs-cosmetic-claim concerns
  • Limited long-term clinical safety data
  • Tobacco-host residual proteins possible
  • Consumer-perception risk for 'growth factor' actives

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.