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Skin Conditioning

NICOTIANA BENTHAMIANA SR-(MOUSE POLYPEPTIDE-4 SH-POLYPEPTIDE-154 DIPEPTIDE-66)

73

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A fusion peptide produced in Nicotiana benthamiana, a tobacco relative widely used for biomanufacturing. Acts as a multi-segment skin conditioner; broadly favourable risk profile but limited public cosmetic data keeps it in Yellow.

Function

SKIN CONDITIONING - EMOLLIENT

Skin benefits

  • Tobacco-plant transient expression — well-established biopharma platform
  • Multi-domain conditioning peptide for skin softness and barrier feel
  • Plant host avoids endotoxin issues of E. coli

Known concerns

  • Possible residual Nicotiana proteins in highly sensitised individuals
  • Limited cosmetic-specific safety data
  • Mouse-derived sequence may raise consumer-perception questions

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related skin conditionings

Same plant / compound family

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.