Other
Nicotine and its salts
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Nicotine and its salts is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.
Nicotine is a pyridine alkaloid found in nightshade plants (especially tobacco) with potent stimulant and vasoconstrictive properties. It is classified as an acute toxic substance (category 2, H300+H310 fatal if swallowed or absorbed through skin) under CLP. The EU Cosmetics Regulation prohibits it from cosmetic products entirely — there is no permitted use level. Nicotine has been used in 'anti-aging' or 'skin tightening' formulations but these uses are illegal in the EU. Its transdermal absorption combined with cardiovascular effects makes it wholly incompatible with cosmetic safety requirements.
Known concerns
- EU Annex II/III prohibited substance — banned in all cosmetic products
- Severe acute toxicity: fatal if swallowed or absorbed through skin (H300, H310)
- Cardiovascular toxicity — vasoconstriction, hypertension, arrhythmia risk
- Highly addictive with neurological effects
- No safe cosmetic use case established
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.