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Skin Conditioning

NICOTINOYL HEXAPEPTIDE-45

Updated
68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A niacin-linked synthetic hexapeptide used at trace levels for tone and radiance claims. No documented hazards but also very limited independent data, so treat marketing claims with caution.

Function

ANTIOXIDANTSKIN PROTECTINGUV FILTER

Skin benefits

  • Niacin-conjugated peptide marketed for skin tone
  • Used at trace levels in leave-on products
  • Generally well tolerated

Known concerns

  • No published independent safety review
  • Manufacturer-supplied claims only
  • Identity and purity supplier-dependent

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.