Skin Conditioning
NICOTINOYL TETRAPEPTIDE-30
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A four-amino-acid peptide capped with a nicotinoyl (vitamin B3) group for skin conditioning. Designer peptide; independent safety data is limited.
Nicotinoyl Tetrapeptide-30 is a tetrapeptide N-terminally conjugated to a nicotinic-acid (niacin) moiety, formulated for cosmetic skin-conditioning use. The niacinoyl cap is intended to extend the well-known activity of vitamin B3 derivatives while improving on-skin stability. Used at parts-per-million levels in serums and creams. No independent CIR or SCCS review of this specific INCI is available; efficacy claims rely on supplier studies. Free niacin can produce flushing in sensitive users at higher concentrations, but the trace-level use here makes that unlikely. Conservative tier: yellow with low evidence.
Function
Skin benefits
- Niacin-derivative skin conditioning
- Trace-level use
- Compatible with most water-based formulas
Known concerns
- Limited independent safety data
- No CIR/SCCS monograph
- Possible mild tingling in sensitive users
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.