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NONOXYNOL-11

CAS 68412-54-4/ 9016-45-9 (generic)/ 37205-87-1 (generic)
26

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

This surfactant is restricted for cosmetic use in the EU due to its classification as an endocrine-disrupting substance family, with the nonylphenyl moiety as the root of regulatory concern.

Nonoxynol-11 is an ethoxylated nonylphenyl ether with an average of 11 ethylene oxide units. It falls within the ethoxylation range that has shown meaningful rates of degradation to nonylphenol under environmental conditions. EU cosmetic regulation under REACH Annex XVII entry 46a restricts nonylphenol and nonylphenol ethoxylates regardless of ethoxylation chain length, and Nonoxynol-11 is included in this restriction.

Known concerns

  • EU REACH Annex XVII restriction in cosmetic products
  • Endocrine disruption via nonylphenyl breakdown
  • Aquatic toxicity and bioaccumulation
  • Environmental persistence

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.