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NONYL NONOXYNOL-11 PHOSPHATE

CAS 39464-64-7
60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Nonyl Nonoxynol-11 Phosphate is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

NONYL NONOXYNOL-11 PHOSPHATE is the phosphate ester of nonoxynol-11, combining the surfactant properties of nonyl phenyl ethoxylate with a phosphate group that enhances emulsification. Nonyl phenyl ethoxylates are under EU regulatory scrutiny due to environmental toxicity of their nonyl phenol degradation products, which are classified as endocrine disruptors under REACH. This substance is not specifically listed in EU cosmetics Annexes II or III, but the nonyl phenyl moiety places it in a restricted category similar to certain fragrance allergens and Annex III substances.

Skin benefits

  • emulsifying
  • surfactant

Known concerns

  • endocrine disruption potential (nonyl phenol metabolite)
  • environmental toxicity
  • phosphate ester sensitivity
  • ethylene oxide contamination (potential)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.