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Hair dye intermediate

O-AMINOPHENOL

CAS 95-55-6
28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Oxidative hair dye intermediate restricted under EU Annex III. PubChem GHS lists multiple acute and irritation hazards, and the substance is a known skin sensitizer with cross-reactivity to other hair dye allergens.

Skin benefits

  • Used as an oxidative hair dye intermediate when permitted
  • SCCS has assessed it under regulated hair dye conditions

Known concerns

  • PubChem GHS classifies as harmful if swallowed, in skin contact, and if inhaled
  • Causes skin irritation and serious eye irritation per GHS
  • Identified as a skin sensitizer in human and animal studies
  • Cross-reactivity reported with p-phenylenediamine sensitized patients
  • Restricted in EU cosmetics under Annex III with strict maximum concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related hair dye intermediates

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.