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o-Toluidine based dyes

22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

O-Toluidine based dyes is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

o-Toluidine based dyes are aromatic amine dyes derived from o-toluidine (2-methylaniline), which is classified as a Category 1A carcinogen by IARC. These dyes can metabolize to release carcinogenic aromatic amines in vivo. EU Regulation 1223/2009 prohibits the use of o-toluidine itself and its derivatives in cosmetic products. The entire class is considered inappropriate for cosmetic use due to the known carcinogenicity of the parent compound.

Known concerns

  • IARC Category 1A carcinogen (o-toluidine parent)
  • Metabolized to carcinogenic amines
  • EU cosmetic prohibition
  • CMR class concern

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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Check your shelf

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Scan any cosmetic product with LuxSense to see if it contains o-Toluidine based dyes and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.