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o-Toluidine based dyes

22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

O-Toluidine based dyes is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

o-Toluidine based dyes are aromatic amine dyes derived from o-toluidine (2-methylaniline), which is classified as a Category 1A carcinogen by IARC. These dyes can metabolize to release carcinogenic aromatic amines in vivo. EU Regulation 1223/2009 prohibits the use of o-toluidine itself and its derivatives in cosmetic products. The entire class is considered inappropriate for cosmetic use due to the known carcinogenicity of the parent compound.

Known concerns

  • IARC Category 1A carcinogen (o-toluidine parent)
  • Metabolized to carcinogenic amines
  • EU cosmetic prohibition
  • CMR class concern

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.