Peptide / synthetic oligopeptide amide
OLIGOPEPTIDE-222 AMIDE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A short synthetic oligopeptide with a C-terminal amide cap used as a skin-conditioning agent in cosmetic products, typically incorporated at sub-percent levels in anti-aging serums and targeted treatments.
Function
Skin benefits
- C-terminal amide modification improves peptide stability
- Synthetic short peptides generally show low irritation in patch testing
- Used at trace levels in cosmetic formulations
- Compatible with sensitive-skin product categories
Known concerns
- No dedicated CIR or SCCS opinion identified
- High peptide number suggests recent introduction with limited literature
- Mechanism and efficacy claims rely on supplier white papers
- Possible synthesis-derived residual contaminants
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related peptide / synthetic oligopeptide amides
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.