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Peptide / synthetic oligopeptide amide

SH-OLIGOPEPTIDE-186 SP AMIDE

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic oligopeptide amide with a linker spacer used as a skin-conditioning ingredient in cosmetic products, typically formulated at sub-percent concentrations within multi-active anti-aging serums.

Function

SKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Synthetic peptide amide with stability-enhancing C-terminal capping
  • Class generally non-sensitizing in patch testing
  • Used at trace levels typical for cosmetic actives
  • Compatible with serum and emulsion bases

Known concerns

  • No dedicated CIR or SCCS opinion for this specific peptide
  • High peptide number indicates newer ingredient with limited literature
  • Mechanism, sequence, and linker chemistry not publicly disclosed
  • Possible residual synthesis impurities at lower purity grades

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related peptide / synthetic oligopeptide amides

65
OLIGOPEPTIDE-222 AMIDE
Peptide / synthetic oligopeptide amide

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.