Conditioning Agent
SH-OLIGOPEPTIDE-186 SP AMIDE
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic peptide analogue of Basic Fibroblast Growth Factor that supports skin repair and cell proliferation, well-established in cosmetic anti-aging applications.
sh-Oligopeptide-186 SP Amide is an 11-amino-acid synthetic peptide modelled after a portion of Basic Fibroblast Growth Factor (bFGF), amidated at the C-terminus for stability. bFGF is a well-characterised growth factor that promotes fibroblast proliferation and wound healing. The synthetic analogue is used in skin conditioning at low concentrations and is not restricted under EU cosmetics regulation, having a well-established safety profile in topical formulations.
Function
Skin benefits
- Supports skin repair and regeneration
- May stimulate fibroblast activity and collagen production
- Anti-aging and skin conditioning benefits
Known concerns
- Growth factor activity requires careful concentration control
- Not recommended for use in broken or compromised skin
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related conditioning agents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.