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Conditioning Agent

OLIGOPEPTIDE-52

83

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic peptide that supports skin conditioning and is generally well-tolerated, though comprehensive long-term safety data is limited compared to older cosmetic ingredients.

Oligopeptide-52 is a synthetic peptide combining nine standard amino acids in an 11-residue chain. It functions as a skin conditioning agent in cosmetic formulations and is not subject to specific EU restrictions under the Cosmetics Regulation. While structurally similar to well-established cosmetic peptides like palmitoyl oligopeptide, its individual safety profile relies on limited published toxicological data.

Function

SKIN CONDITIONING

Skin benefits

  • Supports skin conditioning and texture improvement
  • May stimulate collagen synthesis based on analogy with similar peptide sequences

Known concerns

  • Limited independent safety studies specific to this sequence
  • Potential for sensitisation in susceptible individuals at high concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related conditioning agents

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.